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Zhang W, Xu HJ, Kornblau SM , Drach J, Hu SX, Andreeff M, Benedict WF, Deisseroth AB

Recent evidence has revealed a new mechanism that IL-23, as a strong inducer of AKT/mTOR signal pathway, can inhibit the autophagy activity ofTFCs, resulting in excessive ROS accumulation [97]

Their model integrates cognitive, affective, sleep, and behavioral factors and highlights the importance of coordinated referrals and individualized care strategies

Peer review Peer review information Nature Cell Biology thanks the anonymous reviewers for their contribution to the peer review of this work

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